The course of ALS is very different and individual. The development of the disease is determined by the specific form of progression and the first symptoms of ALS. Of particular importance for the individual assessment of the course is the spread of motor symptoms from one affected region of the body to a subsequent region (topical form of progression) as well as the involvement of the first and second motor neuron (systemic form of progression). The development of ALS can be assessed on the basis of the topical and systemic forms of progression as well as the initial symptoms.
The initial symptoms and the progression forms are displayed in the "Meine Verlaufsform (My progression form)" function in the ALS app. The data on the initial symptoms and the progression forms are transferred to the ALS app from the two studies "NfL (Neurofilament light chain) in ALS" and "id-ALS - Identification of genetic changes in people with ALS".
ALS App Tutorial: Meine Verlaufsform
The Meine Verlaufsform section displays your initial symptoms and the topical and systemic course.
Contact for questions about the progression form
For questions about the progression form, you can call or email us via the Contact Us page.
The initial symptoms describe where the first symptoms appeared. The individual symptoms depend on which motor neuron and which muscle group is more severely affected.
This form of progression describes the spreading pattern of the symptoms. The spread and development of the symptoms is very different and individual.
This form of progression describes the extent of damage to the first and second motor neuron and the resulting motor symptoms.
The currently used progression forms in the ALS app were presented at the APST network meeting and the MND-Net meeting in Berlin from 10 to 11 May 2023. They present the current state of the discussion on the different forms of ALS in Germany.